Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants

Cary W. McConlogue; Daniel Malamud; T. Kyle Vanderlick

doi:10.1016/S0005-2736(98)00052-2

Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants

Cary W. McConlogue, Daniel Malamud, T. Kyle Vanderlick

Research output: Contribution to journal › Article › peer-review

Abstract

We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface. Copyright (C) 1998 Elsevier Science B.V.

Original language	English (US)
Pages (from-to)	124-134
Number of pages	11
Journal	Biochimica et Biophysica Acta - Biomembranes
Volume	1372
Issue number	1
DOIs	https://doi.org/10.1016/S0005-2736(98)00052-2
State	Published - Jun 24 1998

Keywords

Air/water monolayer
Domain shape
Electrostatics
Isotherm
Soluble surfactant

ASJC Scopus subject areas

Biophysics
Biochemistry
Cell Biology

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10.1016/S0005-2736(98)00052-2

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title = "Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants",

abstract = "We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface. Copyright (C) 1998 Elsevier Science B.V.",

keywords = "Air/water monolayer, Domain shape, Electrostatics, Isotherm, Soluble surfactant",

author = "McConlogue, {Cary W.} and Daniel Malamud and Vanderlick, {T. Kyle}",

note = "Funding Information: We gratefully acknowledge the support for this work provided by the David and Lucile Packard Foundation, the Research Foundation of the University of Pennsylvania, the National Science Foundation (CTS-9615868/9622479), and the National Institutes of Health (PO1 AI 37829 to Hershey Medical Center, Hershey, PA).",

year = "1998",

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doi = "10.1016/S0005-2736(98)00052-2",

language = "English (US)",

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T1 - Interaction of DPPC monolayers with soluble surfactants

T2 - electrostatic effects of membrane perturbants

AU - McConlogue, Cary W.

AU - Malamud, Daniel

AU - Vanderlick, T. Kyle

N1 - Funding Information: We gratefully acknowledge the support for this work provided by the David and Lucile Packard Foundation, the Research Foundation of the University of Pennsylvania, the National Science Foundation (CTS-9615868/9622479), and the National Institutes of Health (PO1 AI 37829 to Hershey Medical Center, Hershey, PA).

PY - 1998/6/24

Y1 - 1998/6/24

N2 - We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface. Copyright (C) 1998 Elsevier Science B.V.

AB - We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface. Copyright (C) 1998 Elsevier Science B.V.

KW - Air/water monolayer

KW - Domain shape

KW - Electrostatics

KW - Isotherm

KW - Soluble surfactant

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U2 - 10.1016/S0005-2736(98)00052-2

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JO - Biochimica et Biophysica Acta - Biomembranes

JF - Biochimica et Biophysica Acta - Biomembranes

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Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants

Abstract

Keywords

ASJC Scopus subject areas

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