Interaction of DPPC monolayers with soluble surfactants: electrostatic effects of membrane perturbants

Cary W. McConlogue, Daniel Malamud, T. Kyle Vanderlick

Research output: Contribution to journalArticle

Abstract

We studied the effects of four soluble surfactants on DPPC monolayers to elucidate the action of these membrane perturbants. The presence of nonionic N-9 and amphoteric C31G strongly affected the pure DPPC isotherm, while anionic SDS and cationic DTAB had little effect. The impact of surfactant on DPPC domain shape in the liquid condensed-liquid expanded coexistence region showed the opposite result. Neutral surfactants had minimal effect on the shape of DPPC domains; charged surfactants, on the other hand, induced a new shape transition at high surface pressures previously unreported for DPPC domains. All of these results are discussed with particular attention given to electrostatic effects at the interface. Copyright (C) 1998 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)124-134
Number of pages11
JournalBiochimica et Biophysica Acta - Biomembranes
Volume1372
Issue number1
DOIs
StatePublished - Jun 24 1998

Keywords

  • Air/water monolayer
  • Domain shape
  • Electrostatics
  • Isotherm
  • Soluble surfactant

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Cell Biology

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