Intermolecular interactions in sodium deoxycholate micelles: An NMR study involving a spin-labeled cholestane

G. Esposito, A. Zanobi, E. Giglio, N. V. Pavel, I. D. Campbell

Research output: Contribution to journalArticlepeer-review

Abstract

A 1H and 13C NMR study of the interaction between sodium deoxycholate (NaDC) micelles and a nitroxide probe (cholestane spin-label, CSL) is presented. It is shown that CSL primarily interacts with the β face of NaDC. The 1H NMR relaxation data enable the spatial geometry of the interaction to be defined. van der Waals energy calculations show that the CSL-NaDC interaction corresponds to a minimum if a helical model, previously proposed, is assumed for the NaDC micelle. At high concentrations of CSL, the CSL-NaDC interaction changes and the α face of NaDC may also become involved in the interaction.

Original languageEnglish (US)
Pages (from-to)83-89
Number of pages7
JournalJournal of physical chemistry
Volume91
Issue number1
DOIs
StatePublished - 1987

ASJC Scopus subject areas

  • Engineering(all)
  • Physical and Theoretical Chemistry

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