Is heteropolymer freezing well described by the random energy model?

Vijay S. Pande, Alexander Yu Grosberg, Chris Joerg, Toyoichi Tanaka

    Research output: Contribution to journalArticle


    It is widely held that the random energy model (REM) describes the freezing transition of a variety of types of heteropolymers. We demonstrate that the hallmark property of REM, statistical independence of the energies of states over disorder, is violated in different ways for models commonly employed in heteropolymer freezing studies. The implications for proteins are also discussed.

    Original languageEnglish (US)
    Pages (from-to)3987-3990
    Number of pages4
    JournalPhysical Review Letters
    Issue number21
    StatePublished - May 20 1996


    ASJC Scopus subject areas

    • Physics and Astronomy(all)

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