Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding

Susanne A.I. Seidel, Christoph J. Wienken, Sandra Geissler, Moran Jerabek-Willemsen, Stefan Duhr, Alwin Reiter, Dirk Trauner, Dieter Braun, Philipp Baaske

Research output: Contribution to journalArticle

Original languageEnglish (US)
Pages (from-to)10656-10659
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number42
DOIs
StatePublished - Oct 15 2012

Keywords

  • analytical methods
  • binding affinity
  • label-free methods
  • microscale thermophoresis
  • protein conformation

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

Seidel, S. A. I., Wienken, C. J., Geissler, S., Jerabek-Willemsen, M., Duhr, S., Reiter, A., Trauner, D., Braun, D., & Baaske, P. (2012). Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. Angewandte Chemie - International Edition, 51(42), 10656-10659. https://doi.org/10.1002/anie.201204268