Lack of coincidence between neural and behavioral manifestations of cortical spreading depression

Thomas J. Carew, Terry J. Crow, Lewis F. Petrinovich

Research output: Contribution to journalArticlepeer-review

Abstract

The presence of cortical spreading depression is typically inferred from the presence of hypesthesia. The electrocorticogram and slow-potential change were recorded during cortical spreading depression and it was found that hypesthesia remained long after the cortex recovered from neural depression. Hypesthesia, therefore, is an unreliable indicant of cortical spreading depression; if cortical spreading depression is used as a research tool, neural activity must be monitored. These data offer a special problem for memory transfer studies.

Original languageEnglish (US)
Pages (from-to)1339-1342
Number of pages4
JournalScience
Volume169
Issue number3952
DOIs
StatePublished - 1970

ASJC Scopus subject areas

  • General

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