Lanthanide-based luminescent probes for biological magnesium: accessing polyphosphate-bound Mg2+

Brismar Pinto-Pacheco, Qitian Lin, Claudia W. Yan, Symara de Melo Silva, Daniela Buccella

Research output: Contribution to journalArticlepeer-review


Biomolecule-bound Mg2+ species, particularly polyphosphate complexes, represent a large and dynamic fraction of the total cellular magnesium that is essential for cellular function but remains invisible to most indicators. Here we report a new family of Eu(iii)-based indicators, the MagQEu family, functionalized with a 4-oxo-4H-quinolizine-3-carboxylic acid metal recognition group/sensitization antenna for turn-on, luminescence-based detection of biologically relevant Mg2+ species.

Original languageEnglish (US)
Pages (from-to)3586-3589
Number of pages4
JournalChemical Communications
Issue number24
StatePublished - Feb 28 2023

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


Dive into the research topics of 'Lanthanide-based luminescent probes for biological magnesium: accessing polyphosphate-bound Mg2+'. Together they form a unique fingerprint.

Cite this