Large-Scale CRISPR-Mediated Somatic Mutagenesis Identifies a Signaling Pathway that Guides Retinal Development

Olga Minkina; Claude Desplan

doi:10.1016/j.neuron.2018.03.027

Large-Scale CRISPR-Mediated Somatic Mutagenesis Identifies a Signaling Pathway that Guides Retinal Development

Research output: Contribution to journal › Short survey › peer-review

Abstract

As the mammalian outer retina develops, rod and cone photoreceptors synapse with their respective bipolar cells. Sarin et al. (2018) develop a somatic CRISPR technique to determine how genes differentially expressed among the four cell types mediate outer retina development. As the mammalian outer retina develops, rod and cone photoreceptors synapse with their respective bipolar cells. Sarin et al. develop a somatic CRISPR technique to determine how genes differentially expressed among the four cell types mediate outer retina development.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Neuron
Volume	98
Issue number	1
DOIs	https://doi.org/10.1016/j.neuron.2018.03.027
State	Published - Apr 4 2018

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2018.03.027

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abstract = "As the mammalian outer retina develops, rod and cone photoreceptors synapse with their respective bipolar cells. Sarin et al. (2018) develop a somatic CRISPR technique to determine how genes differentially expressed among the four cell types mediate outer retina development. As the mammalian outer retina develops, rod and cone photoreceptors synapse with their respective bipolar cells. Sarin et al. develop a somatic CRISPR technique to determine how genes differentially expressed among the four cell types mediate outer retina development.",

author = "Olga Minkina and Claude Desplan",

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Large-Scale CRISPR-Mediated Somatic Mutagenesis Identifies a Signaling Pathway that Guides Retinal Development

Abstract

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