Light field otoscope design for 3D in vivo imaging of the middle ear

Noah Bedard, Timothy Shope, Alejandro Hoberman, Mary Ann Haralam, Nader Shaikh, Jelena Kovačević, Nikhil Balram, Ivana Tošić

Research output: Contribution to journalArticlepeer-review

Abstract

We present a light field digital otoscope designed to measure three-dimensional shape of the tympanic membrane. This paper describes the optical and anatomical considerations we used to develop the prototype, along with the simulation and experimental measurements of vignetting, field curvature, and lateral resolution. Using an experimental evaluation procedure, we have determined depth accuracy and depth precision of our system to be 0.05-0.07 mm and 0.21-0.44 mm, respectively. To demonstrate the application of our light field otoscope, we present the first three-dimensional reconstructions of tympanic membranes in normal and otitis media conditions, acquired from children who participated in a feasibility study at the Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center.

Original languageEnglish (US)
Article number#278174
Pages (from-to)260-272
Number of pages13
JournalBiomedical Optics Express
Volume8
Issue number1
DOIs
StatePublished - Jan 1 2017

Keywords

  • Imaging systems
  • Medical and biological imaging

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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