Light scattering study of rheumatoid arthritis

J. Beuthan, U. Netz, O. Minet, A. D. Klose, A. H. Hielscher, A. Scheel, J. Henniger, G. Müller

Research output: Contribution to journalArticlepeer-review


The distribution of fight scattered by finger joints is studied in the near-IR region. It is shown that variations in the optical parameters of the tissue (scattering coefficient μs, absorption coefficient μa, and anisotropy factor g) depend on the presence of the rheumatoid arthritis (RA). At the first stage, the distribution of scattered light was measured in diaphanoscopic experiments. The convolution of a Gaussian error function with the scattering phase function proved to be a good approximation of the data obtained. Then, a new method was developed for the reconstruction of distribution of optical parameters in the finger cross section. Model tests of the quality of this reconstruction method show good results.

Original languageEnglish (US)
Pages (from-to)945-952
Number of pages8
JournalQuantum Electronics
Issue number11
StatePublished - Nov 2002


  • Biomedical functional imaging
  • Near-infrared diaphanoscopy
  • Optical diffusion tomography
  • Rheumatic diseases
  • Scattered light distribution

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Statistical and Nonlinear Physics
  • Atomic and Molecular Physics, and Optics
  • Electrical and Electronic Engineering


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