Light scattering study of rheumatoid arthritis

J. Beuthan, U. Netz, O. Minet, A. D. Klose, A. H. Hielscher, A. Scheel, J. Henniger, G. Müller

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The distribution of fight scattered by finger joints is studied in the near-IR region. It is shown that variations in the optical parameters of the tissue (scattering coefficient μs, absorption coefficient μa, and anisotropy factor g) depend on the presence of the rheumatoid arthritis (RA). At the first stage, the distribution of scattered light was measured in diaphanoscopic experiments. The convolution of a Gaussian error function with the scattering phase function proved to be a good approximation of the data obtained. Then, a new method was developed for the reconstruction of distribution of optical parameters in the finger cross section. Model tests of the quality of this reconstruction method show good results.

    Original languageEnglish (US)
    Pages (from-to)945-952
    Number of pages8
    JournalQuantum Electronics
    Volume32
    Issue number11
    DOIs
    StatePublished - Nov 2002

    Keywords

    • Biomedical functional imaging
    • Near-infrared diaphanoscopy
    • Optical diffusion tomography
    • Rheumatic diseases
    • Scattered light distribution

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Statistical and Nonlinear Physics
    • Atomic and Molecular Physics, and Optics
    • Electrical and Electronic Engineering

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