Localization of polymorphic DNA probes frequently deleted in lung carcinoma

Donna G. Albertson, Paul D. Sherrington, Pamela H. Rabbitts

Research output: Contribution to journalArticlepeer-review

Abstract

Five polymorphic DNA segments from human chromosome 3, that are frequently deleted in lung carcinoma were mapped by non-isotopic in situ hybridization to metaphase chromosomes. The DNA segment D3S3 mapped to 3p13-p14.2, D3S6 to 3p14.3-p14.5, D3S48 to distal 3p21-p22, ERBAß to 3p24.3 and ERBA2 to 3p24.3. The map location of ERBAß and ERBA2 was confirmed by re-mapping each probe in combination with D3S6 as a marker for 3p14.

Original languageEnglish (US)
Pages (from-to)127-132
Number of pages6
JournalHuman Genetics
Volume83
Issue number2
DOIs
StatePublished - Sep 1989

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

Fingerprint

Dive into the research topics of 'Localization of polymorphic DNA probes frequently deleted in lung carcinoma'. Together they form a unique fingerprint.

Cite this