Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative

A. Rullo, A. Reiner, A. Reiter, D. Trauner, E. Y. Isacoff, G. A. Woolley

Research output: Contribution to journalArticlepeer-review

Abstract

A tetra-ortho-chloro substituted azobenzene unit was incorporated into a photoswitchable tethered ligand for ionotropic glutamate receptors. This compound confers the modified protein with the unusual optical responses of the substituted azo scaffold permitting channel opening with yellow and red light and channel closing with blue light.

Original languageEnglish (US)
Pages (from-to)14613-14615
Number of pages3
JournalChemical Communications
Volume50
Issue number93
DOIs
StatePublished - Oct 28 2014

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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