Abstract
Background: Tolosa-Hunt syndrome is a rare clinical syndrome characterized by painful ophthalmoplegia and ipsilateral cranial neuropathies. It is caused by an inflammatory process of unknown etiology. Case presentation: We present a case of a 77-year-old white man with history of Waldenstrom's macroglobulinemia transforming to large B-cell lymphoma who presented to a community physician complaining of 4 months of isolated right retro-orbital pain and later with diplopia, ptosis, 6th nerve and pupil-sparing partial 3rd nerve palsies as well as progressive neurological findings. His clinical course was complicated by debilitating neurological symptoms and multiple hospitalizations leading to a delay in diagnosis caused by incomplete initial workup. Conclusion: This case is a reminder that lymphoproliferative disorders often mimic other neurologic disorders and that Tolosa-Hunt is a rare diagnosis that must be considered a diagnosis of exclusion.
Original language | English (US) |
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Article number | 51 |
Journal | BMC Ophthalmology |
Volume | 15 |
Issue number | 1 |
DOIs | |
State | Published - May 15 2015 |
Keywords
- Cavernous sinus
- Lymphoma
- MRI
- Neuro-imaging
- Tolosa-Hunt
ASJC Scopus subject areas
- Ophthalmology