Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome

Pedro Velasquez; Mai Oudah

doi:10.1007/978-3-031-38079-2_7

Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome

Pedro Velasquez, Mai Oudah

Computer Science

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

As the connection between the gut and brain is further researched, more data has become available, allowing for the utilization of machine learning (ML) in such analysis. In this paper, we explore the relationship between Alzheimer’s disease (AD) and the gut microbiome and how it can be utilized for AD screening. Our main goal is to produce a reliable, noninvasive screening tool for AD. Several ML algorithms are examined separately with and without feature selection/engineering. According to the experimental results, the Naive Bayes (NB) model performs best when trained on a feature set selected by the correlation-based feature selection method, which significantly outperforms the baseline model trained on the original full feature space.

Original language	English (US)
Title of host publication	Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023)
Editors	Miguel Rocha, Florentino Fdez-Riverola, Mohd Saberi Mohamad, Ana Belén Gil-González
Publisher	Springer Science and Business Media Deutschland GmbH
Pages	62-72
Number of pages	11
ISBN (Print)	9783031380785
DOIs	https://doi.org/10.1007/978-3-031-38079-2_7
State	Published - 2023
Event	17th International Conference on Practical Applications of Computational Biology and Bioinformatics, PACBB 2023 - Guimaraes, Portugal Duration: Jul 12 2023 → Jul 14 2023

Publication series

Name	Lecture Notes in Networks and Systems
Volume	743 LNNS
ISSN (Print)	2367-3370
ISSN (Electronic)	2367-3389

Conference

Conference	17th International Conference on Practical Applications of Computational Biology and Bioinformatics, PACBB 2023
Country/Territory	Portugal
City	Guimaraes
Period	7/12/23 → 7/14/23

Keywords

Alzheimer’s disease
Feature Engineering
Feature Selection
Gut Microbiome
Machine Learning

ASJC Scopus subject areas

Control and Systems Engineering
Signal Processing
Computer Networks and Communications

Access to Document

10.1007/978-3-031-38079-2_7

Cite this

Velasquez, P., & Oudah, M. (2023). Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome. In M. Rocha, F. Fdez-Riverola, M. S. Mohamad, & A. B. Gil-González (Eds.), Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023) (pp. 62-72). (Lecture Notes in Networks and Systems; Vol. 743 LNNS). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/978-3-031-38079-2_7

Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome. / Velasquez, Pedro; Oudah, Mai.
Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023). ed. / Miguel Rocha; Florentino Fdez-Riverola; Mohd Saberi Mohamad; Ana Belén Gil-González. Springer Science and Business Media Deutschland GmbH, 2023. p. 62-72 (Lecture Notes in Networks and Systems; Vol. 743 LNNS).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Velasquez, P & Oudah, M 2023, Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome. in M Rocha, F Fdez-Riverola, MS Mohamad & AB Gil-González (eds), Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023). Lecture Notes in Networks and Systems, vol. 743 LNNS, Springer Science and Business Media Deutschland GmbH, pp. 62-72, 17th International Conference on Practical Applications of Computational Biology and Bioinformatics, PACBB 2023, Guimaraes, Portugal, 7/12/23. https://doi.org/10.1007/978-3-031-38079-2_7

Velasquez P, Oudah M. Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome. In Rocha M, Fdez-Riverola F, Mohamad MS, Gil-González AB, editors, Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023). Springer Science and Business Media Deutschland GmbH. 2023. p. 62-72. (Lecture Notes in Networks and Systems). doi: 10.1007/978-3-031-38079-2_7

Velasquez, Pedro ; Oudah, Mai. / Machine Learning Based Screening Tool for Alzheimer’s Disease via Gut Microbiome. Practical Applications of Computational Biology and Bioinformatics, 17th International Conference (PACBB 2023). editor / Miguel Rocha ; Florentino Fdez-Riverola ; Mohd Saberi Mohamad ; Ana Belén Gil-González. Springer Science and Business Media Deutschland GmbH, 2023. pp. 62-72 (Lecture Notes in Networks and Systems).

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