Macromolecular stereochemistry: an example of amplification via cooperation

Mark M. Green, Christopher Andreola, Beth Munoz, Michael P. Reidy

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Poly(n-alkyl isocyanates) have been shown to exist in dilute solution as stiff polymers with a stable helical conformation. The symmetry characteristics of these polymers allow an equal probability for the left (M) and right handed (P) helical senses and in polymers of high enough molecular weight it is expected that helix reversals could separate these regions. The stiff characteristics of poly(n-alkyl isocyanates) suggest helix reversals are rare and therefore that the amplification discussed should be large. Statistical thermodynamic calculations, Predict how the optical activity will depend on the degree of polymerization (N). At high values of N, [α] should be independent of N since helix reversals limit the cooperation while at low N the chain length limits cooperation and thus [α] will depend on N.

Original languageEnglish (US)
Title of host publicationAmerican Chemical Society, Polymer Preprints, Division of Polymer Chemistry
PublisherPubl by ACS
Pages439-440
Number of pages2
Volume30
Edition2
StatePublished - Sep 1989
EventPapers Presented at the Miami Beach, FL Meeting: Polymer Preprints - Miami Beach, FL, USA
Duration: Sep 10 1989Sep 15 1989

Other

OtherPapers Presented at the Miami Beach, FL Meeting: Polymer Preprints
CityMiami Beach, FL, USA
Period9/10/899/15/89

ASJC Scopus subject areas

  • Polymers and Plastics

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    Green, M. M., Andreola, C., Munoz, B., & Reidy, M. P. (1989). Macromolecular stereochemistry: an example of amplification via cooperation. In American Chemical Society, Polymer Preprints, Division of Polymer Chemistry (2 ed., Vol. 30, pp. 439-440). Publ by ACS.