Macroscopic modeling and simulations of supercoiled DNA with bound proteins

Jing Huang; Tamar Schlick

doi:10.1063/1.1511506

Macroscopic modeling and simulations of supercoiled DNA with bound proteins

Jing Huang, Tamar Schlick

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A polymer-level computational model and simulation protocols for supercoiled DNA molecules was developed. The resultant model incorporates the electrostatic and structural properties of DNA molecules with bound proteins based on the well established discrete wormlike chain model for supercoiled DNA.

Original language	English (US)
Pages (from-to)	8573-8586
Number of pages	14
Journal	Journal of Chemical Physics
Volume	117
Issue number	18
DOIs	https://doi.org/10.1063/1.1511506
State	Published - Nov 8 2002

ASJC Scopus subject areas

General Physics and Astronomy
Physical and Theoretical Chemistry

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10.1063/1.1511506

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title = "Macroscopic modeling and simulations of supercoiled DNA with bound proteins",

abstract = "A polymer-level computational model and simulation protocols for supercoiled DNA molecules was developed. The resultant model incorporates the electrostatic and structural properties of DNA molecules with bound proteins based on the well established discrete wormlike chain model for supercoiled DNA.",

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Macroscopic modeling and simulations of supercoiled DNA with bound proteins

Abstract

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