Macroscopic modeling and simulations of supercoiled DNA with bound proteins

Jing Huang, Tamar Schlick

Research output: Contribution to journalArticlepeer-review

Abstract

A polymer-level computational model and simulation protocols for supercoiled DNA molecules was developed. The resultant model incorporates the electrostatic and structural properties of DNA molecules with bound proteins based on the well established discrete wormlike chain model for supercoiled DNA.

Original languageEnglish (US)
Pages (from-to)8573-8586
Number of pages14
JournalJournal of Chemical Physics
Volume117
Issue number18
DOIs
StatePublished - Nov 8 2002

ASJC Scopus subject areas

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

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