Abstract
Sensory systems generally contain a number of neuronal subtypes that express distinct sensory receptor proteins. This diversity is generated through deterministic and stochastic cell fate choices, while maintaining the subtype often requires a distinct mechanism. In a study published in the February 1, 2009, issue of Genes & Development, Lesch and colleagues (pp. 345-358) describe a new transcription factor, NSY-7, that acts to stabilize a stochastic subtype choice in AWC chemo- sensory neurons in Caenorhabditis elegans.
Original language | English (US) |
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Pages (from-to) | 385-390 |
Number of pages | 6 |
Journal | Genes and Development |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Feb 15 2009 |
Keywords
- ; activity-dependent gene expression
- Homeodomain
- Olfactory development
- Transcriptional maintenance
- Transcriptional repression
- cGMP-dependent protein kinase
ASJC Scopus subject areas
- Genetics
- Developmental Biology