Technology, in the form of Intelligent Transportation Systems (ITS), offers a valuable tool to improve the operations and management of our existing transportation facilities. Therefore, the careful and efficient inspection and maintenance of ITS equipment have great importance. ITS device manufacturers, system vendors, suppliers, and contractors, etc., develop and provide drawings, guides, manuals, inspection and maintenance procedures to achieve this important goal. Thus, there is a vast amount of knowledge needed to be extracted and then incorporated into a Manual of Guidelines for effective inspection and maintenance of ITS equipment by knowledgeable, experienced and well-trained inspectors and/or subcontractors. The principal motivation of this study is to develop a state-of-the art and practical ITS Inspection and Maintenance Manual, and to implement this manual in the form of a computer tool. This manual and its computer implementation will be used as a reference document to assist the inspectors, traffic operations, and ITS design and maintenance personnel to ensure effective day-to-day inspection and maintenance of ITS facilities.