Maternal Microbiome and Pregnancy Outcomes That Impact Infant Health: A Review

Anne L. Dunlop, Jennifer G. Mulle, Erin P. Ferranti, Sara Edwards, Alexis B. Dunn, Elizabeth J. Corwin

Research output: Contribution to journalReview articlepeer-review

Abstract

The maternal microbiome is recognized as a key determinant of a range of important maternal and child health outcomes, and together with perinatal factors influences the infant microbiome. This article provides a summary review of research investigating (1) the role of the maternal microbiome in pregnancy outcomes known to adversely influence neonatal and infant health, including preterm birth, cardiometabolic complications of pregnancy such as preeclampsia and gestational diabetes, and excessive gestational weight gain; (2) factors with an established link to adverse pregnancy outcomes that are known to influence the composition of the maternal microbiome; and (3) strategies for promoting a healthy maternal microbiome, recognizing that much more research is needed in this area.

Original languageEnglish (US)
Pages (from-to)377-385
Number of pages9
JournalAdvances in Neonatal Care
Volume15
Issue number6
DOIs
StatePublished - Dec 1 2015

Keywords

  • microbiota
  • pregnancy complications
  • premature birth
  • women's health

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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