Matrix-bound growth factors in tissue repair

Jeffrey A. Hubbell

Research output: Contribution to journalShort surveypeer-review

Abstract

Morphogenesis in tissue development and repair is guided by a variety of signals from the extracellular milieu, including growth factors that are sequestered in the extracellular matrix. Bioengineering approaches have been developed to mimic the natural interactions between growth factors and the extracellular matrix, by engineering biomolecules as novel growth factors and as novel matrix components.

Original languageEnglish (US)
Pages (from-to)387-391
Number of pages5
JournalSwiss Medical Weekly
Volume136
Issue number25-26
StatePublished - Jun 24 2006

Keywords

  • Biomaterials
  • Fibrin
  • Fibrinogen
  • Growth factor
  • Regeneration
  • VEGF

ASJC Scopus subject areas

  • General Medicine

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