Maxillofacial plasmacytoma resulting in intraoral hemorrhage in a patient with multiple myeloma

Oral symptoms of multiple myeloma are common. A patient with refractory multiple myeloma is described because of his unusual orofacial manifestations, including severe intraoral hemorrhage, a massive, erosive maxillofacial lesion with extension into the cranial fossa, and rapid growth of a large intraoral mass. This case report describes the presentation and management of a patient with end‐stage multiple myeloma and severe intraoral hemorrhage. It is interesting because of the rapid growth of the mass, the extension into the para‐nasal sinuses and cranial fossa, and the threatening intraoral hemorrhage. The noninvasive management of this patient's bleeding and evaluation of the mass was essential to minimize the possibility of exacerbating the life‐threatening hemorrhage.