Abstract
We report the effects on pluripotent stem cells proliferation of an antimony salt in chemically amplified negative photoresists (e.g., SU-8, TMMR) commonly used in MEMS fabrications. Since antimony and its derivatives are suspected to be toxic for mammalian cells including mESCs (mouse embryonic stem cells) and hiPSCs (human induced pluripotent stem cells), but it has not yet been investigated. Irrespective of antimony in photoresists, mESCs and hiPSCs cultured on photoresists coated with Matrigel were able to form their colonies and maintain at an undifferentiated state for 7-day culture. The successful 7-day culture is suggested to be ability for investigations of stem cells culture in microfluidic systems.
Original language | English (US) |
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Pages (from-to) | 1233-1236 |
Number of pages | 4 |
Journal | Procedia Engineering |
Volume | 25 |
DOIs | |
State | Published - 2011 |
Event | 25th Eurosensors Conference - Athens, Greece Duration: Sep 4 2011 → Sep 7 2011 |
Keywords
- Cell culture
- Proliferation
- Resist
- Stem cells
ASJC Scopus subject areas
- General Engineering