Micro-electro-fluidic probe for sequential cell sorting and patterning

Ayoola Brimmo, Anoop Menachery, Mohammad A. Qasaimeh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report a dielectrophoresis (DEP) enabled micro-electro-fluidic probe (MeFP) for sequential sorting and patterning of mammalian cells in an open microfluidic system. The MeFP consists of a 3D printed microfluidic probe (MFP) with an array of conductive micro-humps on its tip. Aligning the MeFP in parallel with an indium tin oxide (ITO) coated substrate forms a pin-plate electrode configuration that allows for an integration of DEP forces within the hydrodynamic flow confinement (HFC). Using this setup, target cells are selectively isolated on the micro-hump electrodes and then deposited on the substrate in predefined and controllable micro-patterns.

Original languageEnglish (US)
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages274-275
Number of pages2
ISBN (Electronic)9781733419000
StatePublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: Oct 27 2019Oct 31 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
CountrySwitzerland
CityBasel
Period10/27/1910/31/19

Keywords

  • Cell isolation
  • Cell patterning
  • Dielectrophoresis
  • Microfluidic Probe

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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