TY - JOUR
T1 - Microfluidic Electrokinetic Preconcentration Chips
T2 - Enhancing the detection of nucleic acids and exosomes
AU - Kim, Jongmin
AU - Sahloul, Sarah
AU - Orozaliev, Ajymurat
AU - Do, Vu Q.
AU - Pham, Van Sang
AU - Martins, Diogo
AU - Wei, Xi
AU - Levicky, Rastislav
AU - Song, Yong Ak
PY - 2020/4
Y1 - 2020/4
N2 - Over the past few years, the detection of biological analytes has intensively been studied to understand the biodiagnostics of various diseases [1]. Some of the analytes that have been used as biomarkers for specific diseases include cell-free nucleic acids, (for example, DNA), messenger RNA (mRNA) and microRNA (miRNA) [2]-[5], circulating tumor-specific nucleic acids [circulating tumor DNA (ctDNA) and ctRNA] [6]-[8], exosomes [9], [10], and circulating tumor cells [11]. These biomolecules are known to be effective indicators that can diagnose the presence of a potential disease even if their concentration changes slightly [12].
AB - Over the past few years, the detection of biological analytes has intensively been studied to understand the biodiagnostics of various diseases [1]. Some of the analytes that have been used as biomarkers for specific diseases include cell-free nucleic acids, (for example, DNA), messenger RNA (mRNA) and microRNA (miRNA) [2]-[5], circulating tumor-specific nucleic acids [circulating tumor DNA (ctDNA) and ctRNA] [6]-[8], exosomes [9], [10], and circulating tumor cells [11]. These biomolecules are known to be effective indicators that can diagnose the presence of a potential disease even if their concentration changes slightly [12].
UR - http://www.scopus.com/inward/record.url?scp=85079376778&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85079376778&partnerID=8YFLogxK
U2 - 10.1109/MNANO.2020.2966064
DO - 10.1109/MNANO.2020.2966064
M3 - Article
AN - SCOPUS:85079376778
VL - 14
SP - 18
EP - 34
JO - IEEE Nanotechnology Magazine
JF - IEEE Nanotechnology Magazine
SN - 1932-4510
IS - 2
M1 - 8986548
ER -