TY - GEN
T1 - Microfluidic encryption of on-chip biochemical assays
AU - Ali, Sk Subidh
AU - Ibrahim, Mohamed
AU - Sinanoglu, Ozgur
AU - Chakrabarty, Krishnendu
AU - Karri, Ramesh
PY - 2016
Y1 - 2016
N2 - Recent security analysis of digital micro-fluidic biochips (DMFBs) has revealed that the DMFB design flow is vulnerable to IP piracy, Trojan attacks, overproduction, and counterfeiting. An attacker can launch assay manipulation attacks against DMFBs that are used for clinical diagnostics in healthcare. Moreover, security for lab-on-chip has emerged as an important design criterion in view of the recent findings about spurious test results from Theranos Edison devices. We present encryption based on micro-fluidic multiplexers, wherein an assay is encrypted with a secret-key pattern of fluidic operations. Only an authorized user of the DMFB possesses the secret-key pattern and can get the correct assay outcome. Simulation results show that for practical assays, e.g., protein dilution, an 8-bit secret key is sufficient for overcoming threats to DMFBs.
AB - Recent security analysis of digital micro-fluidic biochips (DMFBs) has revealed that the DMFB design flow is vulnerable to IP piracy, Trojan attacks, overproduction, and counterfeiting. An attacker can launch assay manipulation attacks against DMFBs that are used for clinical diagnostics in healthcare. Moreover, security for lab-on-chip has emerged as an important design criterion in view of the recent findings about spurious test results from Theranos Edison devices. We present encryption based on micro-fluidic multiplexers, wherein an assay is encrypted with a secret-key pattern of fluidic operations. Only an authorized user of the DMFB possesses the secret-key pattern and can get the correct assay outcome. Simulation results show that for practical assays, e.g., protein dilution, an 8-bit secret key is sufficient for overcoming threats to DMFBs.
UR - http://www.scopus.com/inward/record.url?scp=85014183750&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85014183750&partnerID=8YFLogxK
U2 - 10.1109/BioCAS.2016.7833754
DO - 10.1109/BioCAS.2016.7833754
M3 - Conference contribution
AN - SCOPUS:85014183750
T3 - Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016
SP - 152
EP - 155
BT - Proceedings - 2016 IEEE Biomedical Circuits and Systems Conference, BioCAS 2016
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 12th IEEE Biomedical Circuits and Systems Conference, BioCAS 2016
Y2 - 17 October 2016 through 19 October 2016
ER -