MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS

Ayoub Glia; Muhammedin Deliorman; Pavithra Sukumar; Farhad K. Janahi; Bisan Samara; Ayoola T. Brimmo; Mohammad A. Qasaimeh

MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS

Ayoub Glia, Muhammedin Deliorman, Pavithra Sukumar, Farhad K. Janahi, Bisan Samara, Ayoola T. Brimmo, Mohammad A. Qasaimeh

Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Here, an open space (“channel-less”) microfluidic system is developed for capture and analysis of prostate circulating tumor cells (CTCs) in a multiplexed manner. The system consists of a microfluidic probe (MFP) integrated with radially staggered herringbone (HB) elements, named HB-MFP, and a bottom capture substrate functionalized with stripes of different bio-recognition receptors. The HB-MFP scans across the capture substrate in a 2D printing-like manner, and CTCs get captured in a multiplexed manner from whole blood samples.

Original language	English (US)
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	643-644
Number of pages	2
ISBN (Electronic)	9781733419031
State	Published - 2021
Event	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States Duration: Oct 10 2021 → Oct 14 2021

Publication series

Name	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/Territory	United States
City	Palm Springs, Virtual
Period	10/10/21 → 10/14/21

Keywords

3D printing
Circulating tumor cells
Herringbone mixing
Microfluidic probe
Multiplex capture

ASJC Scopus subject areas

Bioengineering
Chemical Engineering (miscellaneous)

Cite this

Glia, A., Deliorman, M., Sukumar, P., Janahi, F. K., Samara, B., Brimmo, A. T., & Qasaimeh, M. A. (2021). MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 643-644). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS. / Glia, Ayoub; Deliorman, Muhammedin; Sukumar, Pavithra et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 643-644 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Glia, A, Deliorman, M, Sukumar, P, Janahi, FK, Samara, B, Brimmo, AT & Qasaimeh, MA 2021, MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 643-644, 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, Palm Springs, Virtual, United States, 10/10/21.

Glia A, Deliorman M, Sukumar P, Janahi FK, Samara B, Brimmo AT et al. MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2021. p. 643-644. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Glia, Ayoub ; Deliorman, Muhammedin ; Sukumar, Pavithra et al. / MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 643-644 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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title = "MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS",

abstract = "Here, an open space (“channel-less”) microfluidic system is developed for capture and analysis of prostate circulating tumor cells (CTCs) in a multiplexed manner. The system consists of a microfluidic probe (MFP) integrated with radially staggered herringbone (HB) elements, named HB-MFP, and a bottom capture substrate functionalized with stripes of different bio-recognition receptors. The HB-MFP scans across the capture substrate in a 2D printing-like manner, and CTCs get captured in a multiplexed manner from whole blood samples.",

keywords = "3D printing, Circulating tumor cells, Herringbone mixing, Microfluidic probe, Multiplex capture",

author = "Ayoub Glia and Muhammedin Deliorman and Pavithra Sukumar and Janahi, {Farhad K.} and Bisan Samara and Brimmo, {Ayoola T.} and Qasaimeh, {Mohammad A.}",

note = "Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",

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language = "English (US)",

series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

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AU - Glia, Ayoub

AU - Deliorman, Muhammedin

AU - Sukumar, Pavithra

AU - Janahi, Farhad K.

AU - Samara, Bisan

AU - Brimmo, Ayoola T.

AU - Qasaimeh, Mohammad A.

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AB - Here, an open space (“channel-less”) microfluidic system is developed for capture and analysis of prostate circulating tumor cells (CTCs) in a multiplexed manner. The system consists of a microfluidic probe (MFP) integrated with radially staggered herringbone (HB) elements, named HB-MFP, and a bottom capture substrate functionalized with stripes of different bio-recognition receptors. The HB-MFP scans across the capture substrate in a 2D printing-like manner, and CTCs get captured in a multiplexed manner from whole blood samples.

KW - 3D printing

KW - Circulating tumor cells

KW - Herringbone mixing

KW - Microfluidic probe

KW - Multiplex capture

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BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

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T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021

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MICROFLUIDIC PROBE FOR MULTIPLEX CAPTURE OF PROSTATE CIRCULATUNG TUMOR CELLS

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

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