MicroParticle photophysics illuminates viral bio-sensing

S. Arnold; R. Ramjit; D. Keng; V. Kolchenko; I. Teraoka

doi:10.1039/b702920a

MicroParticle photophysics illuminates viral bio-sensing

S. Arnold, R. Ramjit, D. Keng, V. Kolchenko, I. Teraoka

Research output: Contribution to journal › Article › peer-review

Abstract

The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere-based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.

Original language	English (US)
Pages (from-to)	65-83
Number of pages	19
Journal	Faraday discussions
Volume	137
DOIs	https://doi.org/10.1039/b702920a
State	Published - 2007

ASJC Scopus subject areas

Physical and Theoretical Chemistry

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10.1039/b702920a

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abstract = "The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere-based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.",

author = "S. Arnold and R. Ramjit and D. Keng and V. Kolchenko and I. Teraoka",

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AU - Kolchenko, V.

AU - Teraoka, I.

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AB - The authors present an approach for specific and rapid unlabeled detection of a virus by using a microsphere-based whispering gallery mode sensor that transduces the interaction of a whole virus with an anchored antibody. They show theoretically that this sensor can detect a single virion below the mass of HIV. A micro-fluidic device is presented that enables the discrimination between viruses of similar size and shape.

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MicroParticle photophysics illuminates viral bio-sensing

Abstract

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