Microrheology as a tool for high-throughput screening

V. Breedveld; D. J. Pine

doi:10.1023/A:1027321232318

Microrheology as a tool for high-throughput screening

V. Breedveld, D. J. Pine

Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Microrheology can be used for high-throughput screening of the rheological properties of sample libraries of complex fluids. Two passive techniques are particularly suitable: video microscopy and diffusing-wave spectroscopy. The techniques complement each other very well and can be applied to samples that offer different experimental challenges. We offer a thorough analysis of the strengths and limitations of microrheology with the emphasis on high-throughput applications. To illustrate the potential of microrheology, results are presented for two representative cases: the rheological screening of aqueous solutions of a block copolypeptide library and the rheological phase diagram of a water/surfactant/salt system.

Original language	English (US)
Pages (from-to)	4461-4470
Number of pages	10
Journal	Journal of Materials Science
Volume	38
Issue number	22
DOIs	https://doi.org/10.1023/A:1027321232318
State	Published - Nov 15 2003

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1023/A:1027321232318

Cite this

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abstract = "Microrheology can be used for high-throughput screening of the rheological properties of sample libraries of complex fluids. Two passive techniques are particularly suitable: video microscopy and diffusing-wave spectroscopy. The techniques complement each other very well and can be applied to samples that offer different experimental challenges. We offer a thorough analysis of the strengths and limitations of microrheology with the emphasis on high-throughput applications. To illustrate the potential of microrheology, results are presented for two representative cases: the rheological screening of aqueous solutions of a block copolypeptide library and the rheological phase diagram of a water/surfactant/salt system.",

author = "V. Breedveld and Pine, {D. J.}",

note = "Funding Information: We would like to thank Dr. Andrew Nowak (UCSB) for synthesizing the diblock copolypeptide library and Megan Valentine (Harvard) for an introduction into IDL-based particle tracking. We further acknowledge financial support of the Netherlands Organization for Scientific Research (NWO), Unilever and the MRSEC Program of the National Science Foundation (DMR00-80034).",

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Microrheology as a tool for high-throughput screening

Abstract

ASJC Scopus subject areas

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