MicroRNA regulation of lipid metabolism

Elena Flowers, Erika Sivarajan Froelicher, Bradley E. Aouizerat

Research output: Contribution to journalReview articlepeer-review

Abstract

MicroRNAs are structural components of an epigenetic mechanism of post-transcriptional regulation of messenger RNA translation. Recently, there is significant interest in the application of microRNA as a blood-based biomarker of underlying physiologic conditions, and the therapeutic administration of microRNA inhibitors and mimics. The purpose of this review is to describe the current body of knowledge on microRNA regulation of genes involved in lipid metabolism, and to introduce the role of microRNA in development and progression of atherosclerosis.

Original languageEnglish (US)
Pages (from-to)12-20
Number of pages9
JournalMetabolism: Clinical and Experimental
Volume62
Issue number1
DOIs
StatePublished - Jan 2013

Keywords

  • Dyslipidemia
  • MicroRNA

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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