MiRò: A miRNA knowledge base

A. Laganà; S. Forte; A. Giudice; M. R. Arena; P. L. Puglisi; R. Giugno; A. Pulvirenti; D. Shasha; A. Ferro

doi:10.1093/database/bap008

MiRò: A miRNA knowledge base

A. Laganà, S. Forte, A. Giudice, M. R. Arena, P. L. Puglisi, R. Giugno, A. Pulvirenti, D. Shasha, A. Ferro

Research output: Contribution to journal › Article › peer-review

Abstract

miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro.

Original language	English (US)
Article number	bap008
Journal	Database
Volume	2009
DOIs	https://doi.org/10.1093/database/bap008
State	Published - 2009

ASJC Scopus subject areas

Information Systems
General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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AU - Laganà, A.

AU - Forte, S.

AU - Giudice, A.

AU - Arena, M. R.

AU - Puglisi, P. L.

AU - Giugno, R.

AU - Pulvirenti, A.

AU - Shasha, D.

AU - Ferro, A.

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AB - miRò is a web-based knowledge base that provides users with miRNA-phenotype associations in humans. It integrates data from various online sources, such as databases of miRNAs, ontologies, diseases and targets, into a unified database equipped with an intuitive and flexible query interface and data mining facilities. The main goal of miRò is the establishment of a knowledge base which allows non-trivial analysis through sophisticated mining techniques and the introduction of a new layer of associations between genes and phenotypes inferred based on miRNAs annotations. Furthermore, a specificity function applied to validated data highlights the most significant associations. The miRò web site is available at: http://ferrolab.dmi.unict.it/miro.

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MiRò: A miRNA knowledge base

Abstract

ASJC Scopus subject areas

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