Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging

Jonghwan Lee, Thomas Pöschinger, Sonia L. Hernandez, Jianzhong Huang, Tessa Johung, Jessica Kandel, Darrell J. Yamashiro, Andreas H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.

    Original languageEnglish (US)
    Title of host publicationProceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010
    DOIs
    StatePublished - 2010
    Event36th Annual Northeast Bioengineering Conference, NEBEC 2010 - New York, NY, United States
    Duration: Mar 26 2010Mar 28 2010

    Publication series

    NameProceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

    Other

    Other36th Annual Northeast Bioengineering Conference, NEBEC 2010
    Country/TerritoryUnited States
    CityNew York, NY
    Period3/26/103/28/10

    ASJC Scopus subject areas

    • Bioengineering

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