Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging

Jonghwan Lee, Thomas Pöschinger, Sonia L. Hernandez, Jianzhong Huang, Tessa Johung, Jessica Kandel, Darrell J. Yamashiro, Andreas H. Hielscher

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.

    Original languageEnglish (US)
    Title of host publicationProceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010
    DOIs
    StatePublished - 2010
    Event36th Annual Northeast Bioengineering Conference, NEBEC 2010 - New York, NY, United States
    Duration: Mar 26 2010Mar 28 2010

    Publication series

    NameProceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

    Other

    Other36th Annual Northeast Bioengineering Conference, NEBEC 2010
    CountryUnited States
    CityNew York, NY
    Period3/26/103/28/10

    ASJC Scopus subject areas

    • Bioengineering

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