Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging

Jonghwan Lee; Thomas Pöschinger; Sonia L. Hernandez; Jianzhong Huang; Tessa Johung; Jessica Kandel; Darrell J. Yamashiro; Andreas H. Hielscher

doi:10.1109/NEBC.2010.5458158

Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging

Jonghwan Lee, Thomas Pöschinger, Sonia L. Hernandez, Jianzhong Huang, Tessa Johung, Jessica Kandel, Darrell J. Yamashiro, Andreas H. Hielscher

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.

Original language	English (US)
Title of host publication	Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010
DOIs	https://doi.org/10.1109/NEBC.2010.5458158
State	Published - 2010
Event	36th Annual Northeast Bioengineering Conference, NEBEC 2010 - New York, NY, United States Duration: Mar 26 2010 → Mar 28 2010

Publication series

Name	Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

Other

Other	36th Annual Northeast Bioengineering Conference, NEBEC 2010
Country/Territory	United States
City	New York, NY
Period	3/26/10 → 3/28/10

ASJC Scopus subject areas

Bioengineering

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10.1109/NEBC.2010.5458158

Cite this

Lee, J., Pöschinger, T., Hernandez, S. L., Huang, J., Johung, T., Kandel, J., Yamashiro, D. J., & Hielscher, A. H. (2010). Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging. In Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010 Article 5458158 (Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010). https://doi.org/10.1109/NEBC.2010.5458158

Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging. / Lee, Jonghwan; Pöschinger, Thomas; Hernandez, Sonia L. et al.
Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010. 2010. 5458158 (Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lee, J, Pöschinger, T, Hernandez, SL, Huang, J, Johung, T, Kandel, J, Yamashiro, DJ & Hielscher, AH 2010, Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging. in Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010., 5458158, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010, 36th Annual Northeast Bioengineering Conference, NEBEC 2010, New York, NY, United States, 3/26/10. https://doi.org/10.1109/NEBC.2010.5458158

Lee J, Pöschinger T, Hernandez SL, Huang J, Johung T, Kandel J et al. Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging. In Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010. 2010. 5458158. (Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010). doi: 10.1109/NEBC.2010.5458158

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title = "Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging",

abstract = "We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.",

author = "Jonghwan Lee and Thomas P{\"o}schinger and Hernandez, {Sonia L.} and Jianzhong Huang and Tessa Johung and Jessica Kandel and Yamashiro, {Darrell J.} and Hielscher, {Andreas H.}",

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AU - Lee, Jonghwan

AU - Pöschinger, Thomas

AU - Hernandez, Sonia L.

AU - Huang, Jianzhong

AU - Johung, Tessa

AU - Kandel, Jessica

AU - Yamashiro, Darrell J.

AU - Hielscher, Andreas H.

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N2 - We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.

AB - We present the results of a study in which we monitored anti-angiogenic therapy response in a mouse cancer model with in-vivo dynamic fluorescence imaging. In the experiments indocyanine green (ICG) was used as a fluorescent optical contrast agent and its time-dependent uptake and washout before and after the administration of bevacizumab was recorded. We found that compared with other organs, tumors showed a noticeable difference in ICG kinetics after treatment.

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U2 - 10.1109/NEBC.2010.5458158

DO - 10.1109/NEBC.2010.5458158

M3 - Conference contribution

AN - SCOPUS:77953070007

SN - 9781424468799

T3 - Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

BT - Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

T2 - 36th Annual Northeast Bioengineering Conference, NEBEC 2010

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ER -

Monitoring of anti-angiogenic drug response with dynamic fluorescence imaging

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