Monofunctionalization of dendrimers with use of microwave-assisted 1,3-dipolar cycloadditions

Yoon Kunsang, Poorva Goyal, Marcus Weck

Research output: Contribution to journalArticlepeer-review

Abstract

Monofunctionalized polyamide-based dendrimers containing either a terminal azide or alkyne moiety have been designed and synthesized via a convergent synthetic approach. The monofunctionalization allows for the single attachment of a functional moiety in quantitative yields by using 1,3-dipolar cycloadditions, thereby opening the possibility for targeted dendrimer functionalization.

Original languageEnglish (US)
Pages (from-to)2051-2054
Number of pages4
JournalOrganic Letters
Volume9
Issue number11
DOIs
StatePublished - May 24 2007

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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