Morphogens: Precise outputs from a variable gradient

Gozde Yucel, Stephen Small

Research output: Contribution to journalShort surveypeer-review


The morphogen gradient as a source of embryonic patterning is one of the best accepted concepts in developmental biology. Morphogens can be transcription factors or extracellular signals, but in both cases, they are thought to provide concentration thresholds that position different cell fates within the developing embryo. Several recent papers examine the patterning activities of Drosophila Bicoid, the first known molecular morphogen and reach different conclusions about the patterning power of a single morphogen gradient.

Original languageEnglish (US)
Pages (from-to)R29-R31
JournalCurrent Biology
Issue number1
StatePublished - Jan 10 2006

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences


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