MRI-fusion biopsy: The contemporary experience

Marc A. Bjurlin, Andrew B. Rosenkrantz, Samir S. Taneja

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    Advancements in magnetic resonance imaging (MRI) and MRI-ultrasound (US)-fusion targeted biopsy have resulted in a paradigm shift in the diagnosis of prostate cancer by overcoming the limitations of systematic biopsy. Prebiopsy MRI and MRI-US-fusion biopsy results in an increased detection of clinically significant disease, reduction in the detection of indolent disease, and allows for tumor localization during targeted biopsy. With these advantages, we have adopted a prebiopsy MRI and MRI-US-fusion biopsy diagnostic care pathway for all men at risk for prostate cancer and have performed more than 1900 biopsies to date. Herein we present our institutional development of MRI-US-fusion biopsy and highlight our results in those men who have had a previous negative biopsy, no prior biopsy, and those with a prior cancer diagnosis who may be candidate for active surveillance. Risk stratification with biomarkers and nomograms may allow for further counseling on the need for biopsy and the risk of harboring clinically significant disease.

    Original languageEnglish (US)
    Pages (from-to)483-489
    Number of pages7
    JournalTranslational Andrology and Urology
    Volume6
    Issue number3
    DOIs
    StatePublished - Jun 1 2017

    Keywords

    • MRI-ultrasound fusion
    • Magnetic resonance imaging (MRI)
    • Pre-biopsy
    • Risk assessment
    • Targeted biopsy

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Urology

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