Much Ado about Zero

Jef D. Boeke, David Fenyo

    Research output: Contribution to journalShort surveypeer-review


    LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

    Original languageEnglish (US)
    Pages (from-to)534-535
    Number of pages2
    Issue number3
    StatePublished - Oct 22 2015

    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)


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