Much Ado about Zero

Jef D. Boeke; David Fenyo

doi:10.1016/j.cell.2015.10.033

Much Ado about Zero

Jef D. Boeke, David Fenyo

Biomedical Engineering

Research output: Contribution to journal › Short survey › peer-review

Abstract

LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

Original language	English (US)
Pages (from-to)	534-535
Number of pages	2
Journal	Cell
Volume	163
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2015.10.033
State	Published - Oct 22 2015

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/j.cell.2015.10.033

Cite this

@article{b3653e67732644bf90def93f9943b95e,

title = "Much Ado about Zero",

abstract = "LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.",

author = "Boeke, {Jef D.} and David Fenyo",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = oct,

day = "22",

doi = "10.1016/j.cell.2015.10.033",

language = "English (US)",

volume = "163",

pages = "534--535",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "3",

}

TY - JOUR

T1 - Much Ado about Zero

AU - Boeke, Jef D.

AU - Fenyo, David

PY - 2015/10/22

Y1 - 2015/10/22

N2 - LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

AB - LINE retrotransposons actively shape mammalian genomes. Denli et al. reveal a new open reading frame, ORF0, on the antisense strand of human LINE-1 encoding a small regulatory protein. This finding may represent the birth of an emerging retrotransposon gene that can adopt various fates, as it can be fused to adjacent host sequences.

UR - http://www.scopus.com/inward/record.url?scp=84956586968&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956586968&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2015.10.033

DO - 10.1016/j.cell.2015.10.033

M3 - Short survey

C2 - 26496595

AN - SCOPUS:84956586968

SN - 0092-8674

VL - 163

SP - 534

EP - 535

JO - Cell

JF - Cell

IS - 3

ER -

Much Ado about Zero

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this