Multi-species integrative biclustering.

Peter Waltman; Thadeous Kacmarczyk; Ashley R. Bate; Daniel B. Kearns; David J. Reiss; Patrick Eichenberger; Richard Bonneau

doi:10.1186/gb-2010-11-9-r96

Multi-species integrative biclustering.

Peter Waltman, Thadeous Kacmarczyk, Ashley R. Bate, Daniel B. Kearns, David J. Reiss, Patrick Eichenberger, Richard Bonneau

Research output: Contribution to journal › Article › peer-review

Abstract

We describe an algorithm, multi-species cMonkey, for the simultaneous biclustering of heterogeneous multiple-species data collections and apply the algorithm to a group of bacteria containing Bacillus subtilis, Bacillus anthracis, and Listeria monocytogenes. The algorithm reveals evolutionary insights into the surprisingly high degree of conservation of regulatory modules across these three species and allows data and insights from well-studied organisms to complement the analysis of related but less well studied organisms.

Original language	English (US)
Pages (from-to)	R96
Journal	Genome biology
Volume	11
Issue number	9
DOIs	https://doi.org/10.1186/gb-2010-11-9-r96
State	Published - 2010

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/gb-2010-11-9-r96

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AU - Waltman, Peter

AU - Kacmarczyk, Thadeous

AU - Bate, Ashley R.

AU - Kearns, Daniel B.

AU - Reiss, David J.

AU - Eichenberger, Patrick

AU - Bonneau, Richard

PY - 2010

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AB - We describe an algorithm, multi-species cMonkey, for the simultaneous biclustering of heterogeneous multiple-species data collections and apply the algorithm to a group of bacteria containing Bacillus subtilis, Bacillus anthracis, and Listeria monocytogenes. The algorithm reveals evolutionary insights into the surprisingly high degree of conservation of regulatory modules across these three species and allows data and insights from well-studied organisms to complement the analysis of related but less well studied organisms.

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SP - R96

JO - Genome biology

JF - Genome biology

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ER -

Multi-species integrative biclustering.

Abstract

ASJC Scopus subject areas

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