Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation

Joshua Fiske; Rupa Patel; Eric Kau; John G. Pappas; Roberto A. Garcia; Samir S. Taneja

doi:10.1016/j.urology.2005.06.122

Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation

Joshua Fiske, Rupa Patel, Eric Kau, John G. Pappas, Roberto A. Garcia, Samir S. Taneja

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

Abstract

Von Hippel-Lindau disease (VHL) is a rare genetic disease with a lifetime risk of clear cell renal cell carcinoma in approximately 70% of cases. We present a case of a 63-year-old man with bilateral, multifocal renal masses. Genetic testing results were consistent with a VHL deletion. The patient had no other disease manifestations consistent with VHL. The patient underwent staged bilateral nephron-sparing procedures. Pathology of all renal masses revealed oncocytoma. To our knowledge, we describe the first reported case of multiple renal oncocytomas in a male patient with a germline VHL mutation.

Original language	English (US)
Pages (from-to)	1320.e11-1320.e12
Journal	Urology
Volume	66
Issue number	6
DOIs	https://doi.org/10.1016/j.urology.2005.06.122
State	Published - Dec 2005

ASJC Scopus subject areas

Urology

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10.1016/j.urology.2005.06.122

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title = "Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation",

abstract = "Von Hippel-Lindau disease (VHL) is a rare genetic disease with a lifetime risk of clear cell renal cell carcinoma in approximately 70% of cases. We present a case of a 63-year-old man with bilateral, multifocal renal masses. Genetic testing results were consistent with a VHL deletion. The patient had no other disease manifestations consistent with VHL. The patient underwent staged bilateral nephron-sparing procedures. Pathology of all renal masses revealed oncocytoma. To our knowledge, we describe the first reported case of multiple renal oncocytomas in a male patient with a germline VHL mutation.",

author = "Joshua Fiske and Rupa Patel and Eric Kau and Pappas, {John G.} and Garcia, {Roberto A.} and Taneja, {Samir S.}",

year = "2005",

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T1 - Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation

AU - Fiske, Joshua

AU - Patel, Rupa

AU - Kau, Eric

AU - Pappas, John G.

AU - Garcia, Roberto A.

AU - Taneja, Samir S.

PY - 2005/12

Y1 - 2005/12

N2 - Von Hippel-Lindau disease (VHL) is a rare genetic disease with a lifetime risk of clear cell renal cell carcinoma in approximately 70% of cases. We present a case of a 63-year-old man with bilateral, multifocal renal masses. Genetic testing results were consistent with a VHL deletion. The patient had no other disease manifestations consistent with VHL. The patient underwent staged bilateral nephron-sparing procedures. Pathology of all renal masses revealed oncocytoma. To our knowledge, we describe the first reported case of multiple renal oncocytomas in a male patient with a germline VHL mutation.

AB - Von Hippel-Lindau disease (VHL) is a rare genetic disease with a lifetime risk of clear cell renal cell carcinoma in approximately 70% of cases. We present a case of a 63-year-old man with bilateral, multifocal renal masses. Genetic testing results were consistent with a VHL deletion. The patient had no other disease manifestations consistent with VHL. The patient underwent staged bilateral nephron-sparing procedures. Pathology of all renal masses revealed oncocytoma. To our knowledge, we describe the first reported case of multiple renal oncocytomas in a male patient with a germline VHL mutation.

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JO - Urology

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ER -

Multifocal renal oncocytoma in a patient with Von Hippel-Lindau mutation

Abstract

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