Abstract
A supramolecular assembly containing an isoguanosine pentaplex with both a "protein-binding" face and a "reporter" face has been generated. When phosphocholine is appended to the proteinbinding face this supramolecular assembly binds multivalently to the pentameric human C-reactive protein, a biomolecule implicated in inflammation and heart disease.
Original language | English (US) |
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Pages (from-to) | 5020-5021 |
Number of pages | 2 |
Journal | Journal of the American Chemical Society |
Volume | 131 |
Issue number | 14 |
DOIs | |
State | Published - Apr 15 2009 |
ASJC Scopus subject areas
- Catalysis
- General Chemistry
- Biochemistry
- Colloid and Surface Chemistry