TY - JOUR
T1 - Music supported therapy promotes motor plasticity in individuals with chronic stroke
AU - Ripollés, P.
AU - Rojo, N.
AU - Grau-Sánchez, J.
AU - Amengual, J. L.
AU - Càmara, E.
AU - Marco-Pallarés, J.
AU - Juncadella, M.
AU - Vaquero, L.
AU - Rubio, F.
AU - Duarte, E.
AU - Garrido, C.
AU - Altenmüller, E.
AU - Münte, T. F.
AU - Rodríguez-Fornells, A.
N1 - Funding Information:
This work was supported by la Fundaci? La Marat? TV3 (Spain), the DFG and FPU program AP2010-4179 to P.R. We are particularly grateful to all the participants for being part of this study. We want to also thank Clara Medrano, Gemma Torres, Gon?alo Padrao, Laura Merino and Sabine Schneider for their help.
Publisher Copyright:
© 2015, Springer Science+Business Media New York.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Novel rehabilitation interventions have improved motor recovery by induction of neural plasticity in individuals with stroke. Of these, Music-supported therapy (MST) is based on music training designed to restore motor deficits. Music training requires multimodal processing, involving the integration and co-operation of visual, motor, auditory, affective and cognitive systems. The main objective of this study was to assess, in a group of 20 individuals suffering from chronic stroke, the motor, cognitive, emotional and neuroplastic effects of MST. Using functional magnetic resonance imaging (fMRI) we observed a clear restitution of both activity and connectivity among auditory-motor regions of the affected hemisphere. Importantly, no differences were observed in this functional network in a healthy control group, ruling out possible confounds such as repeated imaging testing. Moreover, this increase in activity and connectivity between auditory and motor regions was accompanied by a functional improvement of the paretic hand. The present results confirm MST as a viable intervention to improve motor function in chronic stroke individuals.
AB - Novel rehabilitation interventions have improved motor recovery by induction of neural plasticity in individuals with stroke. Of these, Music-supported therapy (MST) is based on music training designed to restore motor deficits. Music training requires multimodal processing, involving the integration and co-operation of visual, motor, auditory, affective and cognitive systems. The main objective of this study was to assess, in a group of 20 individuals suffering from chronic stroke, the motor, cognitive, emotional and neuroplastic effects of MST. Using functional magnetic resonance imaging (fMRI) we observed a clear restitution of both activity and connectivity among auditory-motor regions of the affected hemisphere. Importantly, no differences were observed in this functional network in a healthy control group, ruling out possible confounds such as repeated imaging testing. Moreover, this increase in activity and connectivity between auditory and motor regions was accompanied by a functional improvement of the paretic hand. The present results confirm MST as a viable intervention to improve motor function in chronic stroke individuals.
KW - Chronic stroke
KW - Functional connectivity
KW - Music-supported therapy
KW - Plasticity
KW - fMRI
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U2 - 10.1007/s11682-015-9498-x
DO - 10.1007/s11682-015-9498-x
M3 - Article
C2 - 26707190
AN - SCOPUS:84952008981
SN - 1931-7557
VL - 10
SP - 1289
EP - 1307
JO - Brain Imaging and Behavior
JF - Brain Imaging and Behavior
IS - 4
ER -