Myofascial TMD does not run in families

Karen G. Raphael, Joseph J. Marbach, Rollin M. Gallagher, Bruce P. Dohrenwend

Research output: Contribution to journalArticlepeer-review


This study tests whether facial pain or associated symptoms and disorders aggregates in first degree relatives of those with myofascial temporomandibular disorders (M/TMD). We randomly selected one first degree relative of 106 probands with a lifetime history of M/TMD and one first degree relative of 118 acquaintance control probands with no history of M/TMD. Relatives were directly interviewed about the lifetime occurrence of a broad range of painful and non-painful health conditions and symptoms. Analyses revealed that rates of facial pain, symptoms of TMDs, and a range of other musculoskeletal conditions were not significantly different in first degree relatives of M/TMD probands and first degree relatives of controls. In addition, proband descriptors of facial pain severity or disability did not significantly predict the likelihood of having a first degree relative with one or more TMD-related symptoms. These results indicate that M/TMD is not a familial disorder. Copyright (C) 1999 International Association for the Study of Pain. Published by Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)15-22
Number of pages8
Issue number1-2
StatePublished - Mar 1 1999


  • Familial aggregation
  • Fibromyalgia
  • Genetics
  • Musculoskeletal disorders
  • Pain
  • Temporomandibular disorders

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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