Nanometer-scale siRNA carriers incorporating peptidomimetic oligomers: Physical characterization and biological activity

Engineering & Materials Science

• Oligomers 98%
• Bioactivity 92%
• RNA 82%
• Nanoparticles 52%
• Peptoids 11%
• Genes 9%
• Nanospheres 8%
• Phospholipids 7%
• Cytotoxicity 7%
• Stoichiometry 6%
• Lipids 6%
• Monomers 5%
• Encapsulation 5%
• Water 5%
• Particle size 4%

Chemical Compounds

• Small Interfering RNA 94%
• Peptidomimetic 82%
• Oligomer 54%
• Bioactivity 49%
• Nanoparticle 34%
• Oligonucleotide 16%
• Serum-Free Culture Medium 9%
• Encapsulation 5%
• Phospholipid 5%
• Reaction Stoichiometry 5%
• Dimension 4%
• Lipid 4%
• Monomer 3%

Medicine & Life Sciences

• Small Interfering RNA 57%
• Nanoparticles 55%
• Transfection 19%
• Oligonucleotides 17%
• Gene Silencing 12%
• Peptoids 10%
• Nanospheres 8%
• Water 7%
• Dynamins 7%
• Serum-Free Culture Media 6%
• Particle Size 5%
• Lysosomes 5%
• RNA Interference 5%
• Phospholipids 5%
• RNA 3%
• Lipids 3%