@inproceedings{9cb052db2df7455084bea5c5f0fbe50c,
title = "Nanoscale bio-molecular control using EC-OWLS",
abstract = "A recently developed technique termed {"}Electrochemical Optical Waveguide Lightmode Spectroscopy{"} (EC-OWLS) combines evanescent-field optical sensing with electrochemical control of surface adsorption processes. Initial EC-OWLS investigations efficiently monitored molecular surface adsorption and layer thickness changes of an adsorbed polymer layer examined in situ as a function of potential applied to a waveguide1. A layer of indium tin oxide (ITO) served as both a high retractive index waveguide for optical sensing, and a conductive electrode; an electrochemical flow-through fluid cell incorporated working, reference and counter electrodes. Poly(L-lysine)-grafted-poly(ethylene glycol) (PLL-g-PEG) served as a model, polycation adsorbate. Results indicate that adsorption and desorption of PLL-g-PEG from aqueous buffer are a function of applied potential, and that binding events subsequent to PLL-g-PEG functionalization are dependent on reorganization in the molecular adlayer.",
keywords = "Adsorption, Biosensor, Electrical potential, Indium tin oxide (ito), Polyionic polymers publication searches and indexing",
author = "Bearineer, {J. P.} and J. V{\"o}r{\"o}s and Hubbell, {J. A.} and M. Textor",
year = "2003",
language = "English (US)",
isbn = "0972842209",
series = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003",
pages = "48--51",
editor = "M. Laudon and B. Romanowicz",
booktitle = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003",
note = "2003 Nanotechnology Conference and Trade Show - Nanotech 2003 ; Conference date: 23-02-2003 Through 27-02-2003",
}