Nanotechnology and the double helix

Nadrian C. Seeman

Research output: Contribution to journalReview articlepeer-review


The nonbiological uses of the double-helix structure oF DNA in the building of structures and devices whose essential elements and mechanisms range from 100 nanometers in size are discussed. Regular lattices made of DNA can hold copies of large biological molecules in an ordered array for x-ray crystallography to determine their structure. Alternatively, the lattices can serve as scaffolding for nanoelectronic components, either as a working device or as a step in the manufacture of a device. DNA machines with moving parts can be employed as nanomechanical sensors, switches and tweezers as well as for more elaborate robotic functions.

Original languageEnglish (US)
Pages (from-to)64-75
Number of pages12
JournalScientific American
Issue number6
StatePublished - Jun 2004

ASJC Scopus subject areas

  • General


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