TY - JOUR
T1 - Neurodevelopmental outcome at 8 months and 4 years among infants born full-term small-for-gestational-age
AU - Jelliffe-Pawlowski, Laura L.
AU - Hansen, Robin L.
PY - 2004/8
Y1 - 2004/8
N2 - Objectives: To examine the association between intrauterine growth restriction and neurodevelopmental outcome among full-term small-for-gestational-age (SGAT) infants at 8 months and 4 years of age. Study Design: Growth parameters at birth and test scores on measures of neurodevelopmental function for 3922 children born SGAT were compared with those of 29,369 children born appropriately grown-for-gestational-age term from similar economic backgrounds. Additional within-SGAT/economic group comparisons were made for 1684 SGAT infants with symmetric undergrowth at birth and 2034 SGAT infants with asymmetric undergrowth at birth. Results: Regardless of socioeconomic background, infants born SGAT were found to be at significantly increased risk for neurodevelopmental difficulties at 8 months and at 4 years of age. Few within SGAT/socioeconomic group differences in neurodevelopmental outcome appeared to be associated with specific pattern of growth restriction at birth. Conclusions: The present findings provide further evidence of the individual and public health impact of SGAT birth.
AB - Objectives: To examine the association between intrauterine growth restriction and neurodevelopmental outcome among full-term small-for-gestational-age (SGAT) infants at 8 months and 4 years of age. Study Design: Growth parameters at birth and test scores on measures of neurodevelopmental function for 3922 children born SGAT were compared with those of 29,369 children born appropriately grown-for-gestational-age term from similar economic backgrounds. Additional within-SGAT/economic group comparisons were made for 1684 SGAT infants with symmetric undergrowth at birth and 2034 SGAT infants with asymmetric undergrowth at birth. Results: Regardless of socioeconomic background, infants born SGAT were found to be at significantly increased risk for neurodevelopmental difficulties at 8 months and at 4 years of age. Few within SGAT/socioeconomic group differences in neurodevelopmental outcome appeared to be associated with specific pattern of growth restriction at birth. Conclusions: The present findings provide further evidence of the individual and public health impact of SGAT birth.
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U2 - 10.1038/sj.jp.7211111
DO - 10.1038/sj.jp.7211111
M3 - Article
C2 - 15129225
AN - SCOPUS:4344704594
SN - 0743-8346
VL - 24
SP - 505
EP - 514
JO - Journal of Perinatology
JF - Journal of Perinatology
IS - 8
ER -