Neurotoxins during the Renaissance. Bioarcheology of Ferrante II of Aragon (1469-1496) and Isabella of Aragon (1470-1524)

Clifford Qualls; Raffaella Bianucci; Racquel Legeros; Timothy Bromage; Antonio Lanzirotti; Valentina Giuffra; Ezio Ferroglio; Gino Fornaciari; Otto Appenzeller

doi:10.1016/j.jasrep.2016.01.013

Neurotoxins during the Renaissance. Bioarcheology of Ferrante II of Aragon (1469-1496) and Isabella of Aragon (1470-1524)

Clifford Qualls, Raffaella Bianucci, Racquel Legeros, Timothy Bromage, Antonio Lanzirotti, Valentina Giuffra, Ezio Ferroglio, Gino Fornaciari, Otto Appenzeller

Research output: Contribution to journal › Article › peer-review

Abstract

We show that statistical modeling of analytical results is useful in providing insights into metabolism and disease in bioarcheology. Our results also imply that during the Renaissance in Europe widespread pollution of the biosphere with heavy metals such as mercury and lead affected the Italian nobility at that time.The activity of biologic clocks which control metabolism and autonomic nervous system (ANS) function can be gleaned from the analysis of hair. This provides a means of assessing the health of individuals who lived some six centuries before the present and allows the reconstruction of disease from archived tissues such as hair.

Original language	English (US)
Pages (from-to)	542-546
Number of pages	5
Journal	Journal of Archaeological Science: Reports
Volume	5
DOIs	https://doi.org/10.1016/j.jasrep.2016.01.013
State	Published - Feb 1 2016

Keywords

Archeology
Autonomic nervous system
Biologic rhythms
Environmental pollution
Hair hydrogen isotopes
Lead
Mercury
Modeling
Neurotoxins
Tipping points

ASJC Scopus subject areas

Archaeology
Archaeology

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10.1016/j.jasrep.2016.01.013

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title = "Neurotoxins during the Renaissance. Bioarcheology of Ferrante II of Aragon (1469-1496) and Isabella of Aragon (1470-1524)",

abstract = "We show that statistical modeling of analytical results is useful in providing insights into metabolism and disease in bioarcheology. Our results also imply that during the Renaissance in Europe widespread pollution of the biosphere with heavy metals such as mercury and lead affected the Italian nobility at that time.The activity of biologic clocks which control metabolism and autonomic nervous system (ANS) function can be gleaned from the analysis of hair. This provides a means of assessing the health of individuals who lived some six centuries before the present and allows the reconstruction of disease from archived tissues such as hair.",

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AU - Qualls, Clifford

AU - Bianucci, Raffaella

AU - Legeros, Racquel

AU - Bromage, Timothy

AU - Lanzirotti, Antonio

AU - Giuffra, Valentina

AU - Ferroglio, Ezio

AU - Fornaciari, Gino

AU - Appenzeller, Otto

PY - 2016/2/1

Y1 - 2016/2/1

N2 - We show that statistical modeling of analytical results is useful in providing insights into metabolism and disease in bioarcheology. Our results also imply that during the Renaissance in Europe widespread pollution of the biosphere with heavy metals such as mercury and lead affected the Italian nobility at that time.The activity of biologic clocks which control metabolism and autonomic nervous system (ANS) function can be gleaned from the analysis of hair. This provides a means of assessing the health of individuals who lived some six centuries before the present and allows the reconstruction of disease from archived tissues such as hair.

AB - We show that statistical modeling of analytical results is useful in providing insights into metabolism and disease in bioarcheology. Our results also imply that during the Renaissance in Europe widespread pollution of the biosphere with heavy metals such as mercury and lead affected the Italian nobility at that time.The activity of biologic clocks which control metabolism and autonomic nervous system (ANS) function can be gleaned from the analysis of hair. This provides a means of assessing the health of individuals who lived some six centuries before the present and allows the reconstruction of disease from archived tissues such as hair.

KW - Archeology

KW - Autonomic nervous system

KW - Biologic rhythms

KW - Environmental pollution

KW - Hair hydrogen isotopes

KW - Lead

KW - Mercury

KW - Modeling

KW - Neurotoxins

KW - Tipping points

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Neurotoxins during the Renaissance. Bioarcheology of Ferrante II of Aragon (1469-1496) and Isabella of Aragon (1470-1524)

Abstract

Keywords

ASJC Scopus subject areas

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