New approaches to genomic analysis using single molecules

D. C. Schwartz; T. Anantharaman; C. Aston; B. Mishra; V. Clarke; D. Gebauer; S. Delobette; E. Dimalanta; J. Edington; A. Evenzehav; J. Giacalone; C. Hiort; E. Huff; J. Jing; Z. Lail

doi:10.1145/279069.279124

New approaches to genomic analysis using single molecules

D. C. Schwartz, T. Anantharaman, C. Aston, B. Mishra, V. Clarke, D. Gebauer, S. Delobette, E. Dimalanta, J. Edington, A. Evenzehav, J. Giacalone, C. Hiort, E. Huff, J. Jing, Z. Lail

Computer Science

Research output: Contribution to conference › Paper › peer-review

Abstract

Despite the rapid progress in the human genome project effort, there is little doubt that radically new conceptual approaches are needed before routine whole genome-based analyses can be undertaken by both basic research and clinical laboratories. Physical mapping of genomes, using restriction endonucleases, has played a major role in the identification and characterization of various loci. Optical mapping is the first practical non-electrophoretic genomic mapping approach. It is a single molecule methodology for the rapid production of ordered restriction maps from single DNA molecules.

Original language	English (US)
Pages	248-250
Number of pages	3
DOIs	https://doi.org/10.1145/279069.279124
State	Published - 1998
Event	Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology - New York, NY, USA Duration: Mar 22 1998 → Mar 25 1998

Other

Other	Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology
City	New York, NY, USA
Period	3/22/98 → 3/25/98

ASJC Scopus subject areas

General Computer Science
General Biochemistry, Genetics and Molecular Biology

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10.1145/279069.279124

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Schwartz, D. C., Anantharaman, T., Aston, C., Mishra, B., Clarke, V., Gebauer, D., Delobette, S., Dimalanta, E., Edington, J., Evenzehav, A., Giacalone, J., Hiort, C., Huff, E., Jing, J., & Lail, Z. (1998). New approaches to genomic analysis using single molecules. 248-250. Paper presented at Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology, New York, NY, USA. https://doi.org/10.1145/279069.279124

Schwartz, DC, Anantharaman, T, Aston, C, Mishra, B, Clarke, V, Gebauer, D, Delobette, S, Dimalanta, E, Edington, J, Evenzehav, A, Giacalone, J, Hiort, C, Huff, E, Jing, J & Lail, Z 1998, 'New approaches to genomic analysis using single molecules', Paper presented at Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology, New York, NY, USA, 3/22/98 - 3/25/98 pp. 248-250. https://doi.org/10.1145/279069.279124

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abstract = "Despite the rapid progress in the human genome project effort, there is little doubt that radically new conceptual approaches are needed before routine whole genome-based analyses can be undertaken by both basic research and clinical laboratories. Physical mapping of genomes, using restriction endonucleases, has played a major role in the identification and characterization of various loci. Optical mapping is the first practical non-electrophoretic genomic mapping approach. It is a single molecule methodology for the rapid production of ordered restriction maps from single DNA molecules.",

author = "Schwartz, {D. C.} and T. Anantharaman and C. Aston and B. Mishra and V. Clarke and D. Gebauer and S. Delobette and E. Dimalanta and J. Edington and A. Evenzehav and J. Giacalone and C. Hiort and E. Huff and J. Jing and Z. Lail",

year = "1998",

doi = "10.1145/279069.279124",

language = "English (US)",

pages = "248--250",

note = "Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology ; Conference date: 22-03-1998 Through 25-03-1998",

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T1 - New approaches to genomic analysis using single molecules

AU - Schwartz, D. C.

AU - Anantharaman, T.

AU - Aston, C.

AU - Mishra, B.

AU - Clarke, V.

AU - Gebauer, D.

AU - Delobette, S.

AU - Dimalanta, E.

AU - Edington, J.

AU - Evenzehav, A.

AU - Giacalone, J.

AU - Hiort, C.

AU - Huff, E.

AU - Jing, J.

AU - Lail, Z.

PY - 1998

Y1 - 1998

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AB - Despite the rapid progress in the human genome project effort, there is little doubt that radically new conceptual approaches are needed before routine whole genome-based analyses can be undertaken by both basic research and clinical laboratories. Physical mapping of genomes, using restriction endonucleases, has played a major role in the identification and characterization of various loci. Optical mapping is the first practical non-electrophoretic genomic mapping approach. It is a single molecule methodology for the rapid production of ordered restriction maps from single DNA molecules.

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T2 - Proceedings of the 1998 2nd Annual International Conference on Computational Molecular Biology

Y2 - 22 March 1998 through 25 March 1998

ER -

New approaches to genomic analysis using single molecules

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