New ventures in the construction of complex heterocycles: Synthesis of morphine and hasubanan alkaloids

Dirk Trauner; Stefanie Porth; Till Opatz; Jan W. Bats; Gerald Giester; Johann Mulzer

doi:10.1055/s-1998-5927

New ventures in the construction of complex heterocycles: Synthesis of morphine and hasubanan alkaloids

Dirk Trauner, Stefanie Porth, Till Opatz, Jan W. Bats, Gerald Giester, Johann Mulzer

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Synthetic approaches to morphine and hasubanan alkaloids involving novel reactions for the formation of their dihydrobenzofuran, piperidine and pyrrolidine ring, respectively, are described. The importance of conformational constraints for the success of these reactions is demonstrated. The syntheses of new dioxepanes, diazepanes, dithiocanes, triazenes and dioxonanes are also reported.

Original language	English (US)
Pages (from-to)	653-664
Number of pages	12
Journal	Synthesis
Issue number	SPEC. ISS. APR.
DOIs	https://doi.org/10.1055/s-1998-5927
State	Published - Apr 1998

Keywords

Hasubanan alkaloids
Ketenes
Morphine alkaloids
Total synthesis

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1055/s-1998-5927

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keywords = "Hasubanan alkaloids, Ketenes, Morphine alkaloids, Total synthesis",

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AU - Opatz, Till

AU - Bats, Jan W.

AU - Giester, Gerald

AU - Mulzer, Johann

PY - 1998/4

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AB - Synthetic approaches to morphine and hasubanan alkaloids involving novel reactions for the formation of their dihydrobenzofuran, piperidine and pyrrolidine ring, respectively, are described. The importance of conformational constraints for the success of these reactions is demonstrated. The syntheses of new dioxepanes, diazepanes, dithiocanes, triazenes and dioxonanes are also reported.

KW - Hasubanan alkaloids

KW - Ketenes

KW - Morphine alkaloids

KW - Total synthesis

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IS - SPEC. ISS. APR.

ER -

New ventures in the construction of complex heterocycles: Synthesis of morphine and hasubanan alkaloids

Abstract

Keywords

ASJC Scopus subject areas

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