Next-generation sequencing approaches for genetic mapping of complex diseases

Ferran Casals; Youssef Idaghdour; Julie Hussin; Philip Awadalla

doi:10.1016/j.jneuroim.2011.12.017

Next-generation sequencing approaches for genetic mapping of complex diseases

Ferran Casals, Youssef Idaghdour, Julie Hussin, Philip Awadalla

Research output: Contribution to journal › Review article › peer-review

Abstract

The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.

Original language	English (US)
Pages (from-to)	10-22
Number of pages	13
Journal	Journal of Neuroimmunology
Volume	248
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jneuroim.2011.12.017
State	Published - Jul 15 2012

Keywords

Complex disease
Genomics
Next-generation sequencing

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Neurology
Clinical Neurology

Access to Document

10.1016/j.jneuroim.2011.12.017

Cite this

@article{cdbcbaa3681649d8a194f803f3229520,

title = "Next-generation sequencing approaches for genetic mapping of complex diseases",

abstract = "The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.",

keywords = "Complex disease, Genomics, Next-generation sequencing",

author = "Ferran Casals and Youssef Idaghdour and Julie Hussin and Philip Awadalla",

note = "Funding Information: We thank Simon Gravel for providing curated data on the allelic frequencies from the 1000 Genomes Project. Authors were funded by the Ministry of Development, Exploration and Innovation in Qu{\'e}bec (grant number # PSR-SIIRI-195 ) and a Genome Qu{\'e}bec Award for Population and Medical Genomics to PA.",

year = "2012",

month = jul,

day = "15",

doi = "10.1016/j.jneuroim.2011.12.017",

language = "English (US)",

volume = "248",

pages = "10--22",

journal = "Journal of Neuroimmunology",

issn = "0165-5728",

publisher = "Elsevier",

number = "1-2",

}

TY - JOUR

T1 - Next-generation sequencing approaches for genetic mapping of complex diseases

AU - Casals, Ferran

AU - Idaghdour, Youssef

AU - Hussin, Julie

AU - Awadalla, Philip

N1 - Funding Information: We thank Simon Gravel for providing curated data on the allelic frequencies from the 1000 Genomes Project. Authors were funded by the Ministry of Development, Exploration and Innovation in Québec (grant number # PSR-SIIRI-195 ) and a Genome Québec Award for Population and Medical Genomics to PA.

PY - 2012/7/15

Y1 - 2012/7/15

N2 - The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.

AB - The advent of next generation sequencing technologies has opened new possibilities in the analysis of human disease. In this review we present the main next-generation sequencing technologies, with their major contributions and possible applications to the study of the genetic etiology of complex diseases.

KW - Complex disease

KW - Genomics

KW - Next-generation sequencing

UR - http://www.scopus.com/inward/record.url?scp=84862600977&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84862600977&partnerID=8YFLogxK

U2 - 10.1016/j.jneuroim.2011.12.017

DO - 10.1016/j.jneuroim.2011.12.017

M3 - Review article

C2 - 22285396

AN - SCOPUS:84862600977

SN - 0165-5728

VL - 248

SP - 10

EP - 22

JO - Journal of Neuroimmunology

JF - Journal of Neuroimmunology

IS - 1-2

ER -

Next-generation sequencing approaches for genetic mapping of complex diseases

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this