TY - JOUR
T1 - Nitrate in 2020
T2 - Thirty years from transport to signaling networks
AU - Vidal, Elena A.
AU - Alvarez, José M.
AU - Araus, Viviana
AU - Riveras, Eleodoro
AU - Brooks, Matthew D.
AU - Krouk, Gabriel
AU - Ruffel, Sandrine
AU - Lejay, Laurence
AU - Crawford, Nigel M.
AU - Coruzzi, Gloria M.
AU - Gutiérrez, Rodrigo A.
N1 - Publisher Copyright:
© 2020 ASPB.
PY - 2020/7
Y1 - 2020/7
N2 - Nitrogen (N) is an essential macronutrient for plants and a major limiting factor for plant growth and crop production. Nitrate is the main source of N available to plants in agricultural soils and in many natural environments. Sustaining agricultural productivity is of paramount importance in the current scenario of increasing world population, diversification of crop uses, and climate change. Plant productivity for major crops around the world, however, is still supported by excess application of N-rich fertilizers with detrimental economic and environmental impacts. Thus, understanding how plants regulate nitrate uptake and metabolism is key for developing new crops with enhanced N use efficiency and to cope with future world food demands. The study of plant responses to nitrate has gained considerable interest over the last 30 years. This review provides an overview of key findings in nitrate research, spanning biochemistry, molecular genetics, genomics, and systems biology. We discuss how we have reached our current view of nitrate transport, local and systemic nitrate sensing/signaling, and the regulatory networks underlying nitrate-controlled outputs in plants. We hope this summary will serve not only as a timeline and information repository but also as a baseline to define outstanding questions for future research.
AB - Nitrogen (N) is an essential macronutrient for plants and a major limiting factor for plant growth and crop production. Nitrate is the main source of N available to plants in agricultural soils and in many natural environments. Sustaining agricultural productivity is of paramount importance in the current scenario of increasing world population, diversification of crop uses, and climate change. Plant productivity for major crops around the world, however, is still supported by excess application of N-rich fertilizers with detrimental economic and environmental impacts. Thus, understanding how plants regulate nitrate uptake and metabolism is key for developing new crops with enhanced N use efficiency and to cope with future world food demands. The study of plant responses to nitrate has gained considerable interest over the last 30 years. This review provides an overview of key findings in nitrate research, spanning biochemistry, molecular genetics, genomics, and systems biology. We discuss how we have reached our current view of nitrate transport, local and systemic nitrate sensing/signaling, and the regulatory networks underlying nitrate-controlled outputs in plants. We hope this summary will serve not only as a timeline and information repository but also as a baseline to define outstanding questions for future research.
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U2 - 10.1105/tpc.19.00748
DO - 10.1105/tpc.19.00748
M3 - Review article
C2 - 32169959
AN - SCOPUS:85085123539
VL - 32
SP - 2094
EP - 2119
JO - Plant Cell
JF - Plant Cell
SN - 1040-4651
IS - 7
ER -