Non-equilibrium air plasma for wound bleeding control

Spencer P. Kuo, Cheng Yen Chen, Chuan Shun Lin, Shu Hsing Chiang

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A low temperature non-equilibrium air plasma spray is tested as a blood coagulator. Emission spectroscopy of the plasma effluent indicates that it carries abundant reactive atomic oxygen (RAO), which can activate erythrocyte - platelet interactions to enhance blood coagulation for plug formation. Tests of the device for wound bleeding control were performed on pigs. Four types of wounds, straight cut and cross cut in the ham area, a hole in an ear saphenous vein, and a cut to an ear artery, were examined. The results showed that this plasma spray could effectively stop the bleeding and reduced the bleeding time considerably. Post-Operative observation of straight cut and cross cut wound healing was carried out. It was found that the plasma treatment had a positive impact on wound healing, in particular, of the cross cut wound; its healing time was shortened by a half.

Original languageEnglish (US)
Title of host publicationPlasma for Bio-Decontamination, Medicine and Food Security
EditorsZdenko Machala, Karol Hensel, Yuri Akishev
Number of pages11
StatePublished - 2012

Publication series

NameNATO Science for Peace and Security Series A: Chemistry and Biology
ISSN (Print)1874-6489

ASJC Scopus subject areas

  • General Chemistry
  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Safety, Risk, Reliability and Quality


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