Novel implant design improves implant survival in multirooted extraction sites: A preclinical pilot study

Adi Sivan-Gildor, Eli E. Machtei, Eran Gabay, Shai Frankenthal, Liran Levin, Marcelo Suzuki, Paulo G. Coelho, Hadar Zigdon-Giladi

Research output: Contribution to journalArticlepeer-review


Background: The primary aim is to evaluate clinical, radiographic, and histologic parameters of novel implants with "three roots" design that were inserted into fresh multirooted extraction sockets. A secondary aim is to compare this new implant to standard root-form dental implants. Methods: Immediate implantation of novel or standard design 6 • 6-mm implants was performed bilaterally into multirooted sockets in mandibles of mini-pigs. Twelve weeks later, clinical, radiographic, stability, histomorphometric, and microcomputed tomography (micro-CT) analyses were performed. Results: Survival rates were significantly higher in the test implants compared with control (92.8% versus 33.3%, respectively; P <0.001). Bone loss was greater in the control compared with the test by sounding (mean 3.42 ± 0.68 versus 1.96 ± 0.34 mm) and radiography (mean 3.35 ± 0.62 versus 2.27 ± 0.33 mm). Histologic and micro-CT analyses demonstrated bone fill in the inner part of the test implants. Moreover, bone-to-implant contact was higher in the test implants (55.50% ± 3.68% versus 42.47% ± 9.89%). Contrary to the clinical, radiographic, and histomorphometric results, resonance frequency analysis measurements were greater in the control group (77.74 ± 3.21 implant stability quotient [ISQ]) compared with the test group (31.09 ± 0.28 ISQ), P = 0.008. Conclusions: The novel design implants resulted in significantly greater survival rate in multirooted extraction sites. Further studies will be required to validate these findings.

Original languageEnglish (US)
Pages (from-to)1458-1463
Number of pages6
JournalJournal of periodontology
Issue number10
StatePublished - Oct 1 2014


  • Dental implant design
  • Dental implants
  • Osseointegrated dental implant
  • Short dental implant
  • Survival rates
  • Tooth socket

ASJC Scopus subject areas

  • Periodontics


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